Clinically Occult Squamous Cell Carcinoma of Conjunctiva After Topical Immunotherapy for Ocular Surface Squamous Neoplasia

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topical mitomycin c for partially excised ocular surface squamous neoplasia

purpose : to develop a guideline for the treatment of incompletely removed histopathologically documented ocular surface neoplasia (ossn) with mitomycin c (mmc). materials & methods : through an interventional case series, 17 eyes of 17 patients presented with incompletely removed ossn were treated according to a protocol using 2-3 alternate 7-day courses of mmc 0.04%. clinical recurrence was r...

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Ocular Surface Squamous Neoplasia

The ocular surface is composed of the conjunctiva and the cornea. The conjunctiva is a mucous membrane which covers the globe and inner part of the eyelids. The morphology of conjunctival epithelial cells are nonkeratinized stratified epithelia which vary from cuboidal over the tarsus, to columnar in the fornices, to squamous epithelia on the globe. Goblet cells account for up to 10% of the bas...

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Squamous cell carcinoma of the conjunctiva.

Squamous cell carcinoma of the conjunctiva is the most frequent nonpigmented malignant conjunctival tumor and often misdiagnosed. Chronic unilateral keratoconjunctivitis should be biopsied to rule out malignancy. The authors report 11 cases treated by complete excision with biopsy. 7 cases were followed up 3 months to 7 years without relapse. Beta-irradiation is recommended for cases suspected ...

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Squamous cell carcinoma of the conjunctiva

Introduction and epidemiology Squamous cell carcinoma of the conjunctiva is the end-stage of a spectrum of disease referred to as ocular surface squamous neoplasia (OSSN). OSSN is a malignant disease of the eyes that can lead to loss of vision and, in severe cases, death. The main risk factors for both are exposure to solar ultraviolet radiation outdoors, HIV/AIDS, human papilloma virus and all...

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ژورنال

عنوان ژورنال: Canadian Journal of Ophthalmology

سال: 2017

ISSN: 0008-4182

DOI: 10.1016/j.jcjo.2017.01.009